From discovery to production: Scale-out of continuous flow meso reactors

نویسندگان

  • Peter Styring
  • Ana I R Parracho
چکیده

A continuous flow parallel reactor system has been developed to provide a rapid and seamless transition from the discovery phase and production phase of chemical synthesis, particularly in low volume-high value pharmaceuticals production. Using a single fixed bed catalytic meso reactor, reactions can be screened on a small discovery scale over short time scales. The intensified process produces sufficient material for a full analysis. By replication of the single reactor in parallel, the same chemistry can be achieved on a larger scale, on a small footprint and without the mass and heat transport limitations of reactor scale-out in batch.

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عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2009